When the Famous Five are asked to look after Wilfred, a lonely orphan with a magical ability to communicate with animals, they have no idea of what exciting adventures lie in store. Wilfred is determined to investigate rumours of dastard deeds at a supposed animal 'sanctuary' on the mysterious Whispering Island. He sets off to investigate with four-footed Famous Five member Tim the dog, and the rest of the gang are not far behind. But will they be in time to save the day?